|Student Learning Task
Fundamental Biology Concepts for this Inquiry:
|Recognize science is a processa way of thinking.
|Understand and acknowledge that organ transplantation has a history. Classical experiments and observations led to a number of beliefs (e.g. an organ from one organism cannot be transplanted into another because the animal died). Scientists then began to unravel the mysteries of the immune system. Subsequently this led to anti-rejection drugs, followed by xenotranplantation. Today, scientists are trying to develop a way to transplant cells and organs without the use of anti-rejection drugs.
|Focus on anatomy and physiology of the organ that you choose. How is an organ constructed in order to perform a specific task?
|Understand that an organ functions within a system to maintain homeostasis.
|Understand that an organ within one system has a relationship with a number of other systems within the human organism. These systems function to maintain equilibrium in response to changes within the internal and external environment.
|Identify controllable (lifestyle) and uncontrollable (heredity) factors that could hinder the proper operation of the organ (i.e. disease/disorder).
|Demonstrate how normal functioning of the organ is disrupted by a disease and or disorder.
|Understand the role of the immune system in pathogen protection.
|Understand how organ transplantation can threaten equilibrium within the immune system.
|Understand how drug therapy (anti-rejection drugs) is used to silence the immune response following organ transplantation. Recognize that the inhibition of one system can adversely effect all others.
|Evaluate the ethical implications of organ transplantation in terms of needs, interests and financial support of society on scientific and technological research in this field.